What Is GcMAF?

What is GcMAF and how does it work?

When it comes to GcMAF there is a lot of varying information about it on the internet. Like many non-traditional medical breakthroughs there are strong opinions from many sources and personal interests on it. Here we want to keep things simple and just give you the facts about GcMAF. First of all, let;s breakdown what GcMAF stands for.

What does GcMAFplus® stand for?

Glycoprotein derived




What are Macrophages?

Macrophages are a specific type of white blood cells whose job it is to seek out and destroy abnormal cells. They are also on the clean-up crew when you have tissue damage such as a bruise they will move into the area to clean up dead tissue, but their major job is to find abnormal cells kill them and remove them from the body. GcMAF, occurs naturally in our body and activates macrophages to destroy foreign invaders such as bacteria and viruses, including serious diseases and many viral and non-viral chronic disease are eliminated by macrophages. So basically, GcMAF stimulates the body’s immune system to defend itself. This then prevents diseases from spreading unchecked.

How does GcMAF work?

GcMAF has no side effects and is a naturally occurring protein in humans. It is an essential component to a properly functioning immune system. Essentially it empowers the body to heal itself. GcMAF has 3 sugar molecules attached to it, B and T cells in the body remove one sugar molecule each leaving GcMAF, which has only one sugar molecule remaining.

It is at this point where the positive effects commence…

Disease, cancer, viruses, infections, inflammation or even stress or trauma may succeed in releasing sufficient Nagalase enzyme to incapacitate the Gc protein, which in turn prevents the body from making its own GcMAF. When GcMAF is re-introduced into the body as a treatment or what one would call a replacement therapy, Nagalase does not recognize GcMAF and will not and cannot destroy it.

Transdermal gels

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How long does externally introduced GcMAF last for?

The duration of effectiveness for externally introduced GcMAF when applied topically or sublingually can vary depending on multiple factors. GcMAF, or Glycoprotein Macrophage Activating Factor, is a natural protein that plays a crucial role in immune system regulation. When applied topically or sublingually, its effects may be influenced by factors such as the individual’s health condition, the specific formulation used, and the dosage.

In the case of topical application, GcMAF creams or lotions are absorbed through the skin. The duration of its effects can depend on the formulation’s concentration and the frequency of application. Typically, GcMAF applied topically may have effects that last for several hours to a day, but this can vary. We recommend application twice a day, Individuals with specific skin conditions or therapeutic goals should consult with a healthcare professional for guidance on the appropriate frequency of application.

Sublingual administration involves placing GcMAF drops under the tongue, allowing for rapid absorption into the bloodstream. The duration of effectiveness in this case can also vary. Some individuals may experience relatively quick results, while others might need more time to respond. Our recommendation is twice a day. It’s essential to follow the recommended dosage and frequency prescribed by a healthcare provider to maximize the benefits of sublingual GcMAF administration.

What does new GcMAF do in the body?

The new GcMAF can then again fight bacteria’s, viruses and infections which was it’s original job in the first place. GcMAF is therefore a replacement therapy for those who can’t make their own GcMAF. Taking GcMAF replaces the missing part of the immune system, and acts as the body’s own internal medicine.

Gc protein, also known as vitamin D binding protein (VDBP) or group-specific component (Gc), is a protein found in the bloodstream. It plays a crucial role in the transport of vitamin D and its metabolites throughout the body. Gc protein is primarily synthesized by the liver and then released into the bloodstream.

Its main functions include:

Vitamin D Transport: Gc protein binds to vitamin D and its metabolites, such as 25-hydroxyvitamin D (calcidiol) and 1,25-dihydroxyvitamin D (calcitriol), making them more soluble in blood. This binding helps transport these vitamin D compounds to target tissues where they are needed.

Immune System Modulation: Gc protein has immunomodulatory properties and can affect the immune system. It can influence the activation of macrophages and modulate the immune response. Different forms of Gc protein (such as Gc1 and Gc2) have been associated with varying immune functions.

Serum Biomarker: Gc protein levels in the blood can serve as a biomarker for certain health conditions. For example, low levels of Gc protein have been associated with various diseases and conditions, including malnutrition, chronic kidney disease, and certain cancers.

Drug Binding: Gc protein can also bind to certain drugs and influence their distribution and pharmacokinetics in the body. This can have implications for drug effectiveness and dosage adjustments in some cases.

The primary function of Gc protein is to transport and modulate the activity of vitamin D in the body. It is an essential component of the vitamin D endocrine system, which plays a crucial role in calcium homeostasis, bone health, and immune system regulation.

By reintroducing GcMAF the 20 important actions it is responsible for administering recommence and then the immune system is rebuilt again.

New and safe replacement GcMAF as a vitamin D binding protein works best when taken with high doses of Vitamin D3 coupled with vitamin K2, and a particularly healthy diet and lifestyle, is administered externally and is required until the virus or disease and its nagalase are gone then your own GcMAF starts up again and gets back to work.